50 disses Wayne, Oprah Winfrey and apparently Kanye West in a new record called “Play This on the Radio.”

“First they said that f—-t’s hot, then they let that junkie shine,” 50 raps to lead off the record. “Gave him all the f—in’ trophies, tell me, where the f— is mine?”

As the song closes out, 50 threatens Wayne.

“I’m on your heels, Mr. Carter. I heard you. You want me to ‘die ugly?’ OK. Don’t end up on the list, n—a. Be a missing person like Cam’ron, like Ja [Rule], like [Fat] Joe. Who wants some?”

50 Cent – Play This on The Radio (Wayne Diss)

50 Cent – Shut Your Blood Clot Mouth (Prod. by DJ Premier)

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